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Evolution of the
Prof. Svante Pääbo, PhD
Director of the Genetics Department, Max Planck Institute for Evolutionary Anthropology
To better understand who we are, where we came from, and what “makes humans human”, Prof. Pääbo and his colleagues are creating “miniature brains” genetically engineered to contain Neanderthal DNA.
“Neanderthals are the closest relatives to everyday humans, so if we should define ourselves as a group or a species it is really them that we should compare ourselves to.” – Prof. Svante Pääbo, Director of the genetics department at the Max Planck Institute for Evolutionary Anthropology.
These brain organoids are grown with human stem cells, edited to contain “neanderthalized” versions of several genes. The aim is to identify meaningful differences in human neurobiology.
“We’re seeing if we can find basic differences in how nerve cells function that may be a basis for why humans seem to be cognitively so special.”
The Lindahl Lecture was founded in 2013 in honor of Dr. Sten Lindahl, Chair Emeritus of the Nobel Committee in Physiology or Medicine, Professor Emeritus at Karolinska Institutet, and the kindest, most amazing man you’ll ever meet.
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