Line Jacques, MD, MSc, FRCS(C)

Chief of Peripheral Nerve & Pain Surgery, UCSF Department of Neurological Surgery
Professor and Vice-Chair of Clinical Neurological Surgery, UCSF

Line Jacques, MD, MSc, FRCS(C) is the Chief of Peripheral Nerve and Pain Surgery program at UCSF. Her clinical specialty interests are in the treatment of entrapment syndromes, peripheral nerve tumors, and reconstructive procedures of the peripheral nerves and brachial/lumbosacral plexus. She also has over 2-decades of experience in the treatment of chronic refractory peripheral neuropathic pain.

Early in Dr. Jacques neurosurgery training, she had performed neuromodulation research with Dr. Martinez at Notre Dame Hospital, where they investigated the efficacy of using SCS in the treatment of refractor angina. Dr. Martinez was considered to be one of the early pioneers in spinal cord stimulation and implantable drug delivery systems in Canada. Dr. Jacques work includes the use of spinal cord stimulation in patients with failed back surgery syndrome, complex regional pain syndrome, peripheral vascular disease; occipital nerve stimulation for the treatment of migraines; and implantable drug delivery systems for the treatment of nociceptive pain and movement disorders.She has been involved in several international studies looking at the effectiveness of SCS in FBSS patients vs. CMM with Dr. Kumar, as well as the use of programming algorithms for optimizing back pain coverage using multi-column surgically implanted leads with Dr. Rigouard from France.

Dr. Jacques was recruited by the INESSS (Provincial body responsible for the efficacious use of health care spending in the Province of Quebec) in 2012 to review the current evidence for spinal cord stimulation and implantable drug delivery systems; so that new guidelines for patient access could be developed for the province of Quebec (published June 2013).

Dr. Jacques is presently in charge of the spasticity program, as well as the pain program for augmentative and ablative techniques. She routinely collaborates with the functional neurosurgery, neurology and anesthesia teams.

Sessions at Neurovations Events

2018 Napa Pain Conference

• Individualized Surgical Approaches to Pain Therapies
• Surgical Approaches to Physiological Targets

2017 Napa Pain Conference

• Intrathecal Drug Delivery Systems: No Longer a Novel Therapy, Another Neuromodulation Solution to the Opioid Epidemic

Select Publications

• Southwell DG, Osorio JA, Liverman CS, Friedman LM, Naidu RK, Poree LR, Henry MM, Jacques L. Intrathecal catheter-associated inflammatory mass in a neurofibromatosis type-1 patient receiving fentanyl and bupivacaine. Surg Neurol Int. 2017; 8:159.
• Bray DP, Chan AK, Chin CT, Jacques L. Large Cervical Vagus Nerve Tumor in a Patient with Neurofibromatosis Type 1 Treated with Gross Total Resection: Case Report and Review of the Literature. J Brachial Plex Peripher Nerve Inj. 2016; 11(1):e48-e54.
• Kai-Hong Chan A, Winkler EA, Jacques L.Rate of Perioperative Neurological Complications After Surgery for Cervical Spinal Cord Stimulation. Neurosurgery. 2016 Aug; 63 Suppl 1:150.
• Chan AK, Winkler EA, Jacques L. Rate of perioperative neurological complications after surgery for cervical spinal cord stimulation. J Neurosurg Spine. 2016 Jul; 25(1):31-8.
• Jacques L. Peroneal Intraneural Ganglia Formation Causing Foot Drop in Children: A Clinical Perspective. World Neurosurg. 2016 May; 89:692-3.
• Rigoard P, Jacques L, Delmotte A, Poon K, Munson R, Monlezun O, Roulaud M, Prevost A, Guetarni F, Bataille B, Kumar K. An algorithmic programming approach for back pain symptoms in failed back surgery syndrome using spinal cord stimulation with a multicolumn surgically implanted epidural lead: a multicenter international prospective study. Pain Pract. 2015 Mar; 15(3):195-207.
• Al-Jehani H, Essawi W, Jacques L. Duration of intra-operative stimulation as a predictor of success of spinal cord stimulation for chronic pain syndromes. Turk Neurosurg. 2012; 22(5):588-90.
• Manca A, Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O’Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, Taylor RJ, Goeree R, Sculpher MJ. Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial). Eur J Pain. 2008 Nov; 12(8):1047-58.
• Ahmed-Labib M, Golan JD, Jacques L. Functional outcome of brachial plexus reconstruction after trauma. Neurosurgery. 2007 Nov; 61(5):1016-22; discussion 1022-3.
• Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O’Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, North RB. Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome. Pain. 2007 Nov; 132(1-2):179-88.
• Kumar K, North R, Taylor R, Sculpher M, Van den Abeele C, Gehring M, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O’Callaghan J, Eisenberg E, Milbouw G, Fortini G, Richardson J, Buchser E, Tracey S, Reny P, Brookes M, Sabene S, Cano P, Banks C, Pengelly L, Adler R, Leruth S, Kelly C, Jacobs M. Spinal Cord Stimulation vs. Conventional Medical Management: A Prospective, Randomized, Controlled, Multicenter Study of Patients with Failed Back Surgery Syndrome (PROCESS Study). Neuromodulation. 2005 Oct; 8(4):213-8.